Leveraging Evolving Technology In

Contract Development Service

We accelerate Research and Development activities for our partners by offering formulation development services at cost effective solutions. We provide development services for different dosage forms such as Oral Solids, Injectables, Oral Liquids and Topicals.

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Salient Features

Literature / Patent Review and report

Active Pharmaceutical Ingredients Sourcing and qualification

Inactive Pharmaceutical Ingredients/Excipients, Packing Materials Sourcing and qualification

Pre-formulation Studies

Product Development through QbD approach

Prototype Development

CMAs, CQA and CPPs are identified through DoE

Formulation development of products that require Low Relative Humidity (<30%)

Packaging Development

Optimizing the existing formulation and analytical methods.

Analytical Method Development and Validation

Reverse Engineering Of Reference Product

Technology transfer of product to partner’s preferred manufacturer

Clinical CRO Coordination: Axxelent can coordinate with Clinical CROs to qualify and executing the Pilot/Pivotal BE studies.

Axxelent can provide its expertise to all Technology Transfer and troubleshooting projects at validation levels.

Preclinical and Clinical Phase Product Development for NCEs.

Dosage Form Development Capabilities

Immediate Release Technologies

Film/Sugar coated Tablets

Film-coated tablets are conventional tablets coated with a thin layer of polymer.Sugar coated tablets are compressed tablets that have been coated with concentrated sugar solution.

Oral Disintegrating Tablets

ODT differ from traditional tablets in that they are designed to be dissolved on the tongue rather than swallowed whole.

Chewable Tablets

Chewable tablets are tablets which are difficult to swallow and thus, are chewed within the buccal cavity prior to swallowing.

Sublingual Tablets

Sublingual tablets are tablets that are intended to be dissolved beneath the tongue for absorption through the oral mucosa to produce a systemic effect.

Bilayered Tablets

A bilayer tablet involves the compression of two formulations into a single solid oral tablet, while maintaining a physical separation of the formulations by layering one on top of the other.

Capsules

Dosage form where in which the drug is encapsulated inside the capsule shells.

Modified Release Technologies

Matrix (Hydrophilic/
Hydrophobic polymer) Tablets

Matrix tablets are the type of controlled drug delivery systems, which release the drug in continuous manner. In a matrix system, the drug substance is homogenously mixed into the rate controlling material as crystalline, amorphous or in rare cases molecular dispersion.

Wax Matrix Tablets

These are Matrix type dosage forms wherein which the matrices are prepared by Lipid Waxes and related substacnes.

DR Tablets

Dosage forms that releases the drug only at some point after the initial administration.

IR/MR Tablets

A bilayer tablet involves the compression of two formulations of Immediate release and Modified release into a single solid oral tablet.

DR Pellets

These are pellets which are spherical, free flowing granules with Narrow size range, coated with Delayed release polymer.

Multi Unit Particulate Systems (MUPS)

MUPS is a multiparticulate pharmaceutical solid dosage form produced by compressing a mixture of drug-containing pellets and powder excipients.

Suspensions

A suspension is a heterogeneous mixture in which the solute particles do not dissolve, but get suspended throughout the bulk of the solvent, left floating around freely in the medium.

Solutions

Homogeneous liquid preparations that contain one or more chemical substances dissolved, i.e., molecularly dispersed, in a suitable solvent or mixture of mutually miscible solvents.

Lyophilised vials

Dosage forms which contains freeze dried powder of the product which are reconsituted before adminstration.

Liquid vials

Dosage forms which contains the drug in the liquid forms.

PFS

A pre-filled syringe is a disposable syringe that is supplied already loaded with the substance to be injected.

Ampoules

A hermetically sealed small bulbous glass vessel that is used to hold a Sterile Medical solution for subcutaneous, intramuscular, or intravenous injection.

Gels

Gels are semisolid systems in which there is interaction between colloidal particles within a liquid vehicle.

Creams

Creams are semisolid dosage forms containing water or volatile components and typically less than 50% hydrocarbons, waxes, or polyols as vehicles. They may also contain one or more drug substances dissolved or dispersed in a suitable cream base.

Pastes

Pastes are the semisolid preparations intended for external application to the skin. Usually they are thick and do not melt at normal temperature.

Lotions

Lotions are usually liquid suspensions or dispersions intended for external application to the body.

Oral Solids

Immediate Release Technology

Film/Sugar coated Tablets

Film-coated tablets are conventional tablets coated with a thin layer of polymer.Sugar coated tablets are compressed tablets that have been coated with concentrated sugar solution.

Oral Disintegrating Tablets

ODT differ from traditional tablets in that they are designed to be dissolved on the tongue rather than swallowed whole.

Chewable Tablets

Chewable tablets are tablets which are difficult to swallow and thus, are chewed within the buccal cavity prior to swallowing.

Sublingual Tablets

Sublingual tablets are tablets that are intended to be dissolved beneath the tongue for absorption through the oral mucosa to produce a systemic effect.

Bi-layered Tablets

A bilayer tablet involves the compression of two formulations into a single solid oral tablet, while maintaining a physical separation of the formulations by layering one on top of the other.

Capsules

Dosage form where in which the drug is encapsulated inside the capsule shells.

Modified Release Technologies

Matrix (Hydrophilic/Hydrophobic polymer) Tablets

Matrix tablets are the type of controlled drug delivery systems, which release the drug in continuous manner. In a matrix system, the drug substance is homogenously mixed into the rate controlling material as crystalline, amorphous or in rare cases molecular dispersion.

Wax Matrix Tablets/Granules

These are Matrix type dosage forms wherein which the matrices are prepared by Lipid Waxes and related substacnes.

DR Tablets

Dosage forms that releases the drug only at some point after the initial administration.

IR/MR bilayered Tablets

A bilayer tablet involves the compression of two formulations of Immediate release and Modified release into a single solid oral tablet.

DR Pellets

These are pellets which are spherical, free flowing granules with Narrow size range, coated with Delayed release polymer.

Oral Liquids

Suspensions

A suspension is a heterogeneous mixture in which the solute particles do not dissolve, but get suspended throughout the bulk of the solvent, left floating around freely in the medium.

Solutions

Homogeneous liquid preparations that contain one or more chemical substances dissolved, i.e., molecularly dispersed, in a suitable solvent or mixture of mutually miscible solvents.

Injectables

Lyophilised vials

Dosage forms which contains freeze dried powder of the product which are reconsituted before adminstration.

Liquid vials

Dosage forms which contains the drug in the liquid forms.

PFS

A pre-filled syringe is a disposable syringe that is supplied already loaded with the substance to be injected.

Ampoules

A hermetically sealed small bulbous glass vessel that is used to hold a Sterile Medical solution for subcutaneous, intramuscular, or intravenous injection.

Topicals

Gels

Gels are semisolid systems in which there is interaction between colloidal particles within a liquid vehicle.

Creams

Creams are semisolid dosage forms containing water or volatile components and typically less than 50% hydrocarbons, waxes, or polyols as vehicles. They may also contain one or more drug substances dissolved or dispersed in a suitable cream base.

Pastes

Pastes are the semisolid preparations intended for external application to the skin. Usually they are thick and do not melt at normal temperature.

Lotions

Lotions are usually liquid suspensions or dispersions intended for external application to the body.

Careers

Be a part of a skilled and a fun to work with team.

Contact Us

We are here to help and answer any questions you might have.

Expansion of Phase 2 Manufacturing for Small Volume Parenteral“Axxelent R&D unit received Recognition letter & Registration Certificate from DSIR, Ministry of Science and Technology, Govt. of India”